Acetaminophen CAS#103-90-2

Analgesic & Antipyretic Effects‌:Effective pain relief and fever reduction.


Selective COX Inhibition‌:Modulates COX-2 more than COX-1 at high doses.


Metabolic Versatility‌:Generates reactive metabolites with diverse effects.


Animal Model Efficacy‌:Demonstrated therapeutic properties in vivo.


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Product Description

Products Description of Acetaminophen CAS#103-90-2

Acetaminophen is an analgesic/antipyretic that inhibits COX-2 (83%) and COX-1 (56%) at high 1,000 mg doses. Its toxic metabolite NAPQI causes liver injury by depleting glutathione, and it induces ferroptosis in mouse hepatocytes (reversible by ferrostatin-1). It remains effective for pain and fever relief in animal studies.


Product Applications of Acetaminophen CAS#103-90-2

Acetaminophen (Paracetamol, CAS# 103-90-2) is a non-anti-inflammatory antipyretic/analgesic. Comparable to aspirin in fever relief but weaker in pain relief, it is the top acetanilide derivative ideal for patients intolerant to carboxylic acid drugs. Used for colds and toothaches; also an organic intermediate, H₂O₂ stabilizer and photographic chemical component.

Product Information

Parameters


Melting point

168-172 °C(lit.)

Boiling point

273.17°C (rough estimate)

density

1,293 g/cm3

vapor pressure

0.008Pa at 25℃

refractive index

1.5810 (rough estimate)

Fp

11 °C

storage temp.

Inert atmosphere,Room Temperature

solubility

ethanol: soluble0.5M, clear, colorless

form

Crystals or Crystalline Powder

pka

9.86±0.13(Predicted)

color

White

Odor

odorless

PH

5.5-6.5 (H2O, 20℃)(saturated solution)

PH Range

5.5 - 6.5 (H?O, 20 °C) (saturated solution)

explosive limit

15%(V)

Water Solubility

14 g/L (20 ºC)

Merck

14,47

BRN

2208089

BCS Class

3,4

Cosmetics Ingredients Functions

SKIN CONDITIONING

InChIKey

RZVAJINKPMORJF-UHFFFAOYSA-N

LogP

1.098 at 25℃

CAS DataBase Reference

103-90-2(CAS DataBase Reference)

IARC

3 (Vol. 50, 73) 1999

NIST Chemistry Reference

Acetaminophen(103-90-2)

EPA Substance Registry System

Acetaminophen (103-90-2)


Safety Information


Hazard Codes

Xn,T,F

Risk Statements

22-36/37/38-52/53-36/38-40-39/23/24/25-23/24/25-11

Safety Statements

26-36-61-37/39-22-45-36/37-16-7

RIDADR

UN 3077 9/PG III

WGK Germany

1

RTECS

AE4200000

Autoignition Temperature

540 °C

TSCA

Yes

HazardClass

9

PackingGroup

III

HS Code

29242930

Hazardous Substances Data

103-90-2(Hazardous Substances Data)

Toxicity

LD50 in mice (mg/kg): 338 orally (Starmer), 500 i.p. (Dahlin, Nelson)


Factory Showcase

拼图_美图设计室-(1)

Quality Control Lab

实验室

Shipping And Transportation

拼图_美图设计室

FAQ

Q1: Is Huafeng Chemical a manufacturer or a trader?
A: We are a professional service provider specializing in chemical foreign trade. Rather than being limited to the products of a single factory, we leverage the chemical industry cluster in Shandong Province to integrate production resources from multiple high-quality manufacturers. This allows us to offer a wide range of sourcing options—covering various product categories and origins—instead of simply pushing a single product. Furthermore, our core competitiveness lies in our professional foreign trade services (covering documentation, logistics, and regulatory compliance), ensuring a smooth and worry-free procurement process for you.


Q2: How is the security of my transaction guaranteed when working with Huafeng Chemical?
A: We strictly adhere to international trade rules (Incoterms® 2020) and accept various payment methods, such as Letters of Credit (L/C) and Telegraphic Transfers (T/T). For new clients, we support small-batch trial orders and can clearly define arbitration clauses and applicable laws within the contract. Additionally, we maintain a robust risk management system to help you mitigate common trade risks, such as exchange rate fluctuations, shipping delays, and document discrepancies.


Q3: Do you have experience serving clients in Russian-speaking regions?
A: Yes. We place great importance on the Russian-speaking market; our team includes Russian-speaking business professionals who are well-versed in the import regulations of Russia and the Eurasian Economic Union (EAEU). We understand the importance of EAC certification to clients in these regions and can assist with related compliance inquiries. We have established connections with chemical traders across various CIS countries and have gained valuable experience in specialized packaging and temperature-controlled shipping designed to withstand harsh local winter conditions.


Q4: How do you guarantee product quality?
A: We implement a strict supplier qualification and periodic audit system. A Certificate of Analysis (COA)—issued by the original manufacturer—is provided with every shipment. We also welcome pre-shipment inspections conducted by internationally recognized third-party agencies such as SGS, BV, or ITS. Should the test results fail to meet the standards specified in the contract, you have the right to reject the goods or request a replacement.

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