Bronopol CAS#52-51-7

Effective Antimicrobial AgentBronopol acts as a preservative and biocide, preventing microbial growth in various formulations.


Versatile UsageIt can be incorporated into multiple products, including lubricants and cosmetic or pharmaceutical preparations.


Water-SolubleIts solubility in water allows easy formulation and dispersion in aqueous products.


Stability in FormulationsBronopol maintains antimicrobial efficacy over time, supporting long shelf-life of the products it protects.


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Product Description

Product Application of Bronopol CAS#52-51-7

Bronopol is a formaldehyde-releasing compound and has been identified as a potential allergen for dairy workers. In a reported case, bronopol contained in ultrasound lubricant jelly induced contact dermatitis in a veterinary surgeon.


Product Application of Bronopol CAS#52-51-7

Bronopol is used as an antimicrobial preservative at a concentration of 0.01–0.1% w/v, either alone or blended with other preservatives. It is applied in topical pharmaceuticals, cosmetics and personal care products, with a typical dosage of 0.02% w/v.

Product Information

Parameters


Melting point130-133 °C(lit.)
Boiling point358.0±42.0 °C(Predicted)
density2.0002 (rough estimate)
refractive index1.6200 (estimate)
Fp167°C
storage temp.Inert atmosphere,Room Temperature
solubilityH2O: soluble100mg/mL, clear, colorless to faintly yellow
pka12.02±0.10(Predicted)
formCrystals or Crystalline Powder
colorWhite to yellow
Odorodorless
Water Solubility25 g/100 mL (22 ºC)
Merck141447
BRN1705868
Stability:Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, strong reducing agents, acid chlorides and anhydrides, moisture.
Major Applicationagriculture
cleaning products
cosmetics
environmental
food and beverages
personal care
Cosmetics Ingredients FunctionsPRESERVATIVE
Cosmetic Ingredient Review (CIR)Bronopol (52-51-7)
InChI1S/C3H6BrNO4/c4-3(1-6,2-7)5(8)9/h6-7H,1-2H2
InChIKeyLVDKZNITIUWNER-UHFFFAOYSA-N
SMILESOCC(Br)(CO)[N+]([O-])=O
LogP1.150 (est)
CAS DataBase Reference52-51-7(CAS DataBase Reference)
NIST Chemistry ReferenceBronopol(52-51-7)
EPA Substance Registry SystemBronopol (52-51-7)


Safety Information


Hazard CodesXn,N
Risk Statements21/22-37/38-41-50
Safety Statements26-37/39-61-36/37/39
RIDADRUN 3241 4.1/PG 3
WGK Germany2
RTECSTY3385000
F4.2-8-9-21
TSCATSCA listed
HazardClass4.1
PackingGroupIII
HS Code29055999
Storage Class4.1B - Flammable solid hazardous materials
Hazard ClassificationsAcute Tox. 4 Dermal
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
Hazardous Substances Data52-51-7(Hazardous Substances Data)
ToxicityLD50 in mice, rats (mg/kg): 350, 400 orally (Croshaw)


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FAQ

Q1: Is Huafeng Chemical a manufacturer or a trader?
A: We are a professional service provider specializing in chemical foreign trade. Rather than being limited to the products of a single factory, we leverage the chemical industry cluster in Shandong Province to integrate production resources from multiple high-quality manufacturers. This allows us to offer a wide range of sourcing options—covering various product categories and origins—instead of simply pushing a single product. Furthermore, our core competitiveness lies in our professional foreign trade services (covering documentation, logistics, and regulatory compliance), ensuring a smooth and worry-free procurement process for you.


Q2: How is the security of my transaction guaranteed when working with Huafeng Chemical?
A: We strictly adhere to international trade rules (Incoterms® 2020) and accept various payment methods, such as Letters of Credit (L/C) and Telegraphic Transfers (T/T). For new clients, we support small-batch trial orders and can clearly define arbitration clauses and applicable laws within the contract. Additionally, we maintain a robust risk management system to help you mitigate common trade risks, such as exchange rate fluctuations, shipping delays, and document discrepancies.


Q3: Do you have experience serving clients in Russian-speaking regions?
A: Yes. We place great importance on the Russian-speaking market; our team includes Russian-speaking business professionals who are well-versed in the import regulations of Russia and the Eurasian Economic Union (EAEU). We understand the importance of EAC certification to clients in these regions and can assist with related compliance inquiries. We have established connections with chemical traders across various CIS countries and have gained valuable experience in specialized packaging and temperature-controlled shipping designed to withstand harsh local winter conditions.


Q4: How do you guarantee product quality?
A: We implement a strict supplier qualification and periodic audit system. A Certificate of Analysis (COA)—issued by the original manufacturer—is provided with every shipment. We also welcome pre-shipment inspections conducted by internationally recognized third-party agencies such as SGS, BV, or ITS. Should the test results fail to meet the standards specified in the contract, you have the right to reject the goods or request a replacement.

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