Metronidazole CAS#443-48-1

Effective Anti-anaerobic Activity:Metronidazole has strong bactericidal effects against a wide range of anaerobic microorganisms.


Dual-action Mechanism:Both the drug and its metabolites inhibit bacterial DNA synthesis, effectively stopping bacterial growth and reproduction.


Clinically Proven Efficacy:Recognized by the World Health Organization as a key treatment for anaerobic infections with significant therapeutic results.


Broad Therapeutic Applications:Widely used for the prevention and treatment of various infections, including oral, respiratory, gastrointestinal, abdominal, skin, and systemic infections caused by anaerobic bacteri.

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Product Description

Product Description of Metronidazole CAS#443-48-1

Metronidazole is a nitroimidazole antibiotic active against anaerobic bacteria and Giardia, working by inhibiting bacterial DNA synthesis after metabolic activation. Designated by WHO in 1978 as the drug of choice for anaerobic infections, it was first used for vaginal trichomoniasis and is now widely applied to prevent and treat anaerobic infections throughout the body.


Product Application of Metronidazole CAS#443-48-1

This product has been used since 1959 for the treatment of vaginal trichomoniasis, and since 1970 for intestinal and extraintestinal amoebiasis. It is characterized by high efficacy, low toxicity, and a broad range of applications. However, animal studies have shown potential mutagenic and teratogenic effects.

Metronidazole exhibits strong antibacterial activity against most anaerobic bacteria. It is widely used in the treatment of amoebiasis, trichomoniasis, and various anaerobic infections.


Product Information

Parameters


Melting point159-161 °C (lit.)
Boiling point301.12°C (rough estimate)
density1.3994 (rough estimate)
refractive index1.5800 (estimate)
Fp9℃
storage temp.2-8°C
solubilityacetic acid: 0.1 M, clear, faintly yellow
formcrystalline
pkapKa 2.62(H2O,t =25±0.2,Iundefined) (Uncertain)
colorwhite to light yellow
Water Solubility<0.1 g/100 mL at 20 ºC
Merck146157
BRN611683
BCS Class1,3
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyVAOCPAMSLUNLGC-UHFFFAOYSA-N
LogP-0.02
IARC2B (Vol. 13, Sup 7) 1987
NIST Chemistry ReferenceMetronidazole(443-48-1)
EPA Substance Registry SystemMetronidazole (443-48-1)
Hazard CodesXn
Risk Statements40-46-45-39/23/24/25-23/24/25-11
Safety Statements36/37-45-53-16-7
WGK Germany3
RTECSNI5600000
F8
HS Code29332990
Hazardous Substances Data443-48-1(Hazardous Substances Data)


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A: Yes. We place great importance on the Russian-speaking market; our team includes Russian-speaking business professionals who are well-versed in the import regulations of Russia and the Eurasian Economic Union (EAEU). We understand the importance of EAC certification to clients in these regions and can assist with related compliance inquiries. We have established connections with chemical traders across various CIS countries and have gained valuable experience in specialized packaging and temperature-controlled shipping designed to withstand harsh local winter conditions.


Q4: How do you guarantee product quality?
A: We implement a strict supplier qualification and periodic audit system. A Certificate of Analysis (COA)—issued by the original manufacturer—is provided with every shipment. We also welcome pre-shipment inspections conducted by internationally recognized third-party agencies such as SGS, BV, or ITS. Should the test results fail to meet the standards specified in the contract, you have the right to reject the goods or request a replacement.

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