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5-Bromo-2-chloropyrimidine CAS#32779-36-5
Valuable Pharmaceutical Intermediate: Widely used in the synthesis of macitentan, an endothelin receptor antagonist for pulmonary hypertension treatment.
Reactive Halogenated Structure: Contains both chloro and bromo substituents, enabling versatile chemical transformations and functionalization.
High Synthetic Utility: The pyrimidine core structure supports efficient incorporation into complex drug molecules.
Supports Advanced Drug Development: Facilitates the production of targeted therapeutic agents, making it important for modern pharmaceutical research.
Product Description
Product Description of 5-Bromo-2-chloropyrimidine CAS#32779-36-5
5-Bromo-2-chloropyrimidine is a halogenated pyrimidine derivative featuring chloro and bromo substituents at the 2- and 5-positions of the ring. It is primarily used as a pharmaceutical intermediate in the synthesis of macitentan, an endothelin receptor antagonist employed in the treatment of pulmonary hypertension.
Product Applications of 5-Bromo-2-chloropyrimidine CAS#32779-36-5
5-Bromo-2-chloropyrimidine is used as a pharmaceutical intermediate in the synthesis of various drug compounds, including inhibitors. It is also utilized in cross-coupling reactions involving indium organometallic reagents with 2,5-dihalopyrimidines.
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