Fluconazole CAS#86386-73-4

Broad-Spectrum Antifungal Activity:Fluconazole provides effective inhibition against a wide range of fungal pathogens, making it suitable for multiple antifungal applications.


Systemic Antifungal EfficacyAs a systemic antifungal agent, it delivers reliable therapeutic performance throughout the body for deep and systemic fungal infections.


Highly Selective Mechanism of ActionIt selectively inhibits fungal cytochrome P-450-dependent enzymes, ensuring targeted antifungal activity with high specificity.


Potent Inhibition of Fungal Sterol SynthesisFluconazole strongly and specifically blocks fungal sterol biosynthesis, disrupting fungal cell membrane formation and preventing growth.


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Product Description

Product Description of Fluconazole CAS#86386-73-4

Fluconazole is an advanced triazole antifungal medication initially developed by Pfizer Pharmaceuticals in the United States. It offers broad-spectrum antifungal activity and is designed for systemic use. Fluconazole selectively targets and inhibits fungal cytochrome P-450-dependent enzymes, and it is also a powerful and specific inhibitor of fungal alcohol synthesis.

Product Application of Fluconazole CAS#86386-73-4

Fluconazole is a broad-spectrum triazole antifungal drug with an antibacterial spectrum similar to ketoconazole. It is long-acting, highly effective against deep fungal infections, and provides strong antifungal activity with good oral absorption. It is mainly used for the treatment of candidiasis and cryptococcosis, and is also effective for oropharyngeal candidiasis in cancer patients.

Product Information

Parameters


Melting point138-140°C
Boiling point579.8±60.0 °C(Predicted)
density1.05
Fp9℃
storage temp.2-8°C
solubilityDMSO: 5 mg/mL
formsolid
pkapKa 1.76±0.1(H2O t=24 I=0.1(NaCl)) (Uncertain)
colorWhite to Off-White
Water Solubility1g/L(temperature not stated)
Merck144122
BCS Class1,3
InChIInChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2
InChIKeyRFHAOTPXVQNOHP-UHFFFAOYSA-N
SMILESC1(C=CC(F)=CC=1F)C(O)(CN1N=CN=C1)CN1N=CN=C1
CAS DataBase Reference86386-73-4(CAS DataBase Reference)


Safety Information


Hazard CodesXn,Xi,T,F
Risk Statements22-36/37/38-20/21/22-39/23/24/25-23/24/25-11
Safety Statements26-36-36/37/39-24/25-45-36/37-16-7
RIDADRUN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany3
RTECSXZ4810000
HS Code29336990
Hazardous Substances Data86386-73-4(Hazardous Substances Data)


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Q1: Is Huafeng Chemical a manufacturer or a trader?
A: We are a professional service provider specializing in chemical foreign trade. Rather than being limited to the products of a single factory, we leverage the chemical industry cluster in Shandong Province to integrate production resources from multiple high-quality manufacturers. This allows us to offer a wide range of sourcing options—covering various product categories and origins—instead of simply pushing a single product. Furthermore, our core competitiveness lies in our professional foreign trade services (covering documentation, logistics, and regulatory compliance), ensuring a smooth and worry-free procurement process for you.


Q2: How is the security of my transaction guaranteed when working with Huafeng Chemical?
A: We strictly adhere to international trade rules (Incoterms® 2020) and accept various payment methods, such as Letters of Credit (L/C) and Telegraphic Transfers (T/T). For new clients, we support small-batch trial orders and can clearly define arbitration clauses and applicable laws within the contract. Additionally, we maintain a robust risk management system to help you mitigate common trade risks, such as exchange rate fluctuations, shipping delays, and document discrepancies.


Q3: Do you have experience serving clients in Russian-speaking regions?
A: Yes. We place great importance on the Russian-speaking market; our team includes Russian-speaking business professionals who are well-versed in the import regulations of Russia and the Eurasian Economic Union (EAEU). We understand the importance of EAC certification to clients in these regions and can assist with related compliance inquiries. We have established connections with chemical traders across various CIS countries and have gained valuable experience in specialized packaging and temperature-controlled shipping designed to withstand harsh local winter conditions.


Q4: How do you guarantee product quality?
A: We implement a strict supplier qualification and periodic audit system. A Certificate of Analysis (COA)—issued by the original manufacturer—is provided with every shipment. We also welcome pre-shipment inspections conducted by internationally recognized third-party agencies such as SGS, BV, or ITS. Should the test results fail to meet the standards specified in the contract, you have the right to reject the goods or request a replacement.

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