Gentamicin sulfate CAS#1405-41-0

Broad-spectrum bactericidal antibiotic effective against Gram-negative bacteria such as Escherichia coli, Shigella dysenteriae, Klebsiella pneumoniae, Proteus, and Pseudomonas aeruginosa.


Versatile administration routes: suitable for systemic or local infections, oral use for intestinal infections, and ophthalmic use for conjunctivitis and keratitis.


Can be used prophylactically or therapeutically in combination with other antibiotics (e.g., metronidazole or clindamycin) to reduce infection rates in colon surgery.


Shares a similar antibacterial spectrum with kanamycin, making it a reliable option for treating various bacterial infections.



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Product Description

Product Description of Gentamicin sulfate CAS#1405-41-0

Gentamicin sulfate is a glycoside bactericidal antibiotic with an antibacterial spectrum similar to kanamycin. It mainly treats infections caused by various Gram-negative bacteria. It is used topically for eye inflammation, orally for intestinal infections and preoperative bowel preparation, and combined with other drugs to lower colon surgery infection risks.


Product Application of Gentamicin sulfate CAS#1405-41-0

Gentamicin sulfate treats various bacterial infections induced by susceptible Gram-negative bacteria and staphylococci.
It inhibits bacterial protein synthesis by binding to 30S ribosomal subunit. It also damages bacterial outer membrane to kill pseudomonas. It is widely applied for sepsis, urinary tract infections, endocarditis and other bacterial disorders.

Product Information

Parameters


Melting point218-237°C
alphaD25 +102°
density1.000 g/cm3
storage temp.2-8°C
solubilityH2O: 50 mg/mL As stock solution, store at −20°C. Stable at 37°C for 5 days.
formpowder
colorcolorless to light yellow
Odorodorless
PH4.0-5.5 (0.1g/mL in H2O)
optical activity[α]20/D +110±8°, c = 1% in H2O
biological sourceMicromonospora purpurea
Water SolubilitySoluble in water
Merck134403
InChIKeyRDEIXVOBVLKYNT-HDZPSJEVSA-N
CAS DataBase Reference1405-41-0(CAS DataBase Reference)
EPA Substance Registry SystemGentamicin sulfate (1405-41-0)
Hazard CodesXn
Risk Statements42/43
Safety Statements23-36/37-45-22-24/25
WGK Germany2
RTECSLY2625000
F3
HS Code29419010
ToxicityLD50 in mice (mg base/kg): 430 i.p.; 485 s.c.; 75 i.v.; >9050 orally (Black)


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Q1: Is Huafeng Chemical a manufacturer or a trader?
A: We are a professional service provider specializing in chemical foreign trade. Rather than being limited to the products of a single factory, we leverage the chemical industry cluster in Shandong Province to integrate production resources from multiple high-quality manufacturers. This allows us to offer a wide range of sourcing options—covering various product categories and origins—instead of simply pushing a single product. Furthermore, our core competitiveness lies in our professional foreign trade services (covering documentation, logistics, and regulatory compliance), ensuring a smooth and worry-free procurement process for you.


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A: We strictly adhere to international trade rules (Incoterms® 2020) and accept various payment methods, such as Letters of Credit (L/C) and Telegraphic Transfers (T/T). For new clients, we support small-batch trial orders and can clearly define arbitration clauses and applicable laws within the contract. Additionally, we maintain a robust risk management system to help you mitigate common trade risks, such as exchange rate fluctuations, shipping delays, and document discrepancies.


Q3: Do you have experience serving clients in Russian-speaking regions?
A: Yes. We place great importance on the Russian-speaking market; our team includes Russian-speaking business professionals who are well-versed in the import regulations of Russia and the Eurasian Economic Union (EAEU). We understand the importance of EAC certification to clients in these regions and can assist with related compliance inquiries. We have established connections with chemical traders across various CIS countries and have gained valuable experience in specialized packaging and temperature-controlled shipping designed to withstand harsh local winter conditions.


Q4: How do you guarantee product quality?
A: We implement a strict supplier qualification and periodic audit system. A Certificate of Analysis (COA)—issued by the original manufacturer—is provided with every shipment. We also welcome pre-shipment inspections conducted by internationally recognized third-party agencies such as SGS, BV, or ITS. Should the test results fail to meet the standards specified in the contract, you have the right to reject the goods or request a replacement.

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